- How many babies are born with osteogenesis imperfecta?
- How is OI diagnosed?
- Who is most likely to get osteogenesis imperfecta?
- Is Oi a disability?
- What is OI type 4?
- Is Osteogenesis Imperfecta a type of dwarfism?
- What’s wrong with the Baxter baby?
- Is Osteogenesis Imperfecta painful?
- What percent of the population has osteogenesis imperfecta?
- What is the life expectancy of someone with osteogenesis imperfecta?
- What organs are affected by osteogenesis imperfecta?
How many babies are born with osteogenesis imperfecta?
OI can sometimes be life-threatening if it occurs in babies either before or shortly after birth.
Approximately one person in 20,000 will develop brittle bone disease.
It occurs equally among males and females and among ethnic groups..
How is OI diagnosed?
The diagnosis of OI is made on the basis of family history and/or clinical presentation. Frequent fractures, short stature, a blue hue to the white part of the eye (blue sclera), teeth problems (dentinogenesis imperfecta) and hearing loss that progresses after puberty may be present.
Who is most likely to get osteogenesis imperfecta?
Osteogenesis imperfecta occurs equally in girls and boys and among all racial and ethnic groups, affecting six to seven people in every 100,000. An estimated 20,000 to 50,000 people in the U.S. have the condition. The estimated number varies greatly because milder forms of osteogenesis imperfecta can go undiagnosed.
Is Oi a disability?
Most people with OI experience physical disability. OI also can cause weak muscles, brittle teeth, a curved spine, and hearing loss. Most forms of OI are caused by abnormal genes that are passed down from one or both parents to their children. There are currently 11 types of OI.
What is OI type 4?
Osteogenesis imperfecta type IV is a moderate type of osteogenesis imperfecta (OI; see this term), a genetic disorder characterized by increased bone fragility, low bone mass and susceptibility to bone fractures.
Is Osteogenesis Imperfecta a type of dwarfism?
Osteogenesis imperfecta (OI) Type III is a dwarfism condition, with adults generally reaching a height of three feet, although profound short stature is often associated with the other three types as well.
What’s wrong with the Baxter baby?
When you listen to 3-year-old Byron Baxter laugh and talk, you’d never know anything was wrong with him. But he was born with a rare condition called osteogenesis imperfecta, or brittle bone disease.
Is Osteogenesis Imperfecta painful?
Background: Pain is a common symptom of osteogenesis imperfecta (OI) among children and adolescents.
What percent of the population has osteogenesis imperfecta?
Osteogenesis imperfecta affects approximately 1 in 10,000 to 20,000 people worldwide. An estimated 25,000 to 50,000 people in the United States have the condition.
What is the life expectancy of someone with osteogenesis imperfecta?
The median survival time in the OI cohort was 72.4 years for males (compared to 81.5 years in the reference population) and 77.4 for females (compared to 84.5 in the reference population).
What organs are affected by osteogenesis imperfecta?
In more severe forms of osteogenesis imperfecta, there may be bone deformities, poor lung development and lung problems, a barrel-shaped chest, poor muscle development in the arms and legs. Osteogenesis imperfecta is caused by a faulty gene that affects the body’s ability to produce collagen.